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Sorafenib

  • Sorafenib
Sorafenib

Sorafenib

  • Name: Sorafenib free base
  • CAS#: 284461-73-0 (free base)
  • Chemical Formula: C21H16ClF3N4O3
  • Molecular Weight: 464.82
  • 产品描述:Sorafenib is a synthetic compound targeting growth signaling and angiogenesis.Sorafenib was approved in 2005 for use in the treatment of advanced renal cancer.
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Sorafenib tosylate

CAS# 475207-59-1 (tosylate)



Related CAS #: 475207-59-1 (tosylate) 284461-73-0 (free base)

Synonym: BAY 439006; BAY439006; BAY-439006; BAY 439006 Tosylate Salt; BAY 549085; Nexavar; SFN.

IUPAC/Chemical Name: 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide

InChi Key: MLDQJTXFUGDVEO-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)

SMILES Code: O=C(C1=NC=CC(OC2=CC=C(C=C2)NC(NC3=CC=C(C(C(F)(F)F)=C3)Cl)=O)=C1)NC

Appearance: white solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


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